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Binding of an intramolecular biosensor or of a relatively abundant intermolecular biosensor introduces observer effects in which the dynamics of the target molecule under study are significantly perturbed, whereas binding of a sparingly expressed intermolecular biosensor is subject to a saturation effect, where the pool of unbound biosensor is significantly depleted.
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Beckett, the Nobel Prize winning playwright, who died in 1989, expressed himself sparingly: 14 minutes for "Not I"; 12 minutes for "Ohio Impromptu"; seven minutes for "Catastrophe"; 45 seconds for "Breath," and so on.
Acquired as a free agent on Aug. 13, Lowe had only been used sparingly, and when he expressed his pessimism about making the roster in the middle of September, he may have been right.
While some have expressed hope that President Obama will use the privilege more sparingly in lawsuits challenging his own administration's conduct, that prospect seems counter-intuitive at best.
Yet, though it was a form of propaganda, as a fable it did manage to express Ali's real ambivalence about his hometown of Louisville, a place to which he has only sparingly returned.
Show pictures sparingly.
Feed sparingly.
But sparingly.
Apply sparingly.
Pulse sparingly.
Cry sparingly.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com