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A last proposal would be that, once XRCC4 ensues its function of DNA ligase IV stabilization (most of the mutations described spare expression of DNA ligase IV to some extent), it becomes dispensable during immune system development while still required in other DNA damage response situations such as in the brain.
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But Robert E. Rubin, the former Treasury secretary, faced withering questions from the panel, the Financial Crisis Inquiry Commission, for his spare expressions of remorse.
The loss of nigral dopaminergic neurons is also relatively selective as dopaminergic neurons of the adjacent VTA (A10 nucleus) are spared despite expression of G2019S LRRK2 in this population.
In contrast to the Q128-Htt-induced loss of function of the small LNv, large LNv appear to be spared following expression of Q128-Htt, as shown both by physiological and morphological assays.
Here, we show that removing vSPNs spares the expression of symmetric tail undulations.
Previous studies also showed that removing Mauthner cells and their homologs, while drastically increasing the response delay of escape turns, spared the expression of a wide spectrum of turning angles [ 6, 9].
Earlier model tenements had been spare in exterior expression, but Atterbury, with the goal of better ventilation of the interior court, gave his a heroic four-story-high archway.
In contrast, later-onset (E11.5) activation of Phox2b∆8 expression spared NA neuron development and was not perinatal respiratory-lethal, despite loss of the RTN.
He has the look of Bruce Lee down pat, with the same defiant expression and spare but muscled frame.
What he did, with means so modest and expression so spare and affecting, as a twenty-three year-old black man struggling in a country riven by economic depression and racism, remains stunning and enduring, and a reminder to us now of how much we have left to do.
More recently, there has been an increased use of recombinant toxic proteins designed to target T cells with high CD25 expression (but spares T lymphocytes not involved in immune suppression).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com