This problem is exacerbated by the pronounced spare receptor effect of IL-1.
Although our experiments were performed with high concentrations of IL-1 that far exceed physiological levels, IL-1 is a potent cytokine with a strong spare receptor effect.
Too much cortisol secretion leads to the accumulation of fat around the torso - the spare tire effect.
In an early March interview, Kuok replied: "In a meltdown of this intensity, I don't think anyone is really spared; the effect on everyone's financial results will be adverse".
But thousands of Americans received samples from their doctors, and nearly two dozen American children were born with missing or misshapen limbs; American women were not spared its effects.
Some, in the most heavily affected areas, have seen their unsafe homes demolished and have been forced to move to suburbs that were spared the effects of the violent quake.
Bacteria have a system that allows tetracyclines to be transported into the cell, whereas human cells do not; human cells therefore are spared the effects of tetracycline on protein synthesis.
Crouched there, hands clasped behind our necks, noses to the linoleum, we were expected to accept on faith that in this prescribed posture, as good little citizens of the goodest country on earth, we would be spared the effects of any disaster, natural or nuclear.
These tanks, spared the effects of the bombing, slowed the advance of the Polish 1st Armoured Division, preventing a breakthrough east of the road.
The economy recovers, the total material loss for Guinea, Liberia, and Sierra Leone is "only" one hundred million dollars, and the rest of the world is spared the effects of Ebola.
Considered the breadbasket of South Sudan, the region sits close to the capital in the southern part of the country, and until recently it had been spared the effects of the civil war.
