Sentence examples for spanning many genes from inspiring English sources

However, despite ever greater numbers of sequenced genomes, most genome-wide association studies cannot distinguish causal variants from linked passenger mutations spanning many genes.

Later, several other loci spanning many genes were discovered in AD using GWL scans.

More recently, attempts to reconstruct the phylogeny of mollusks were based on concatenated matrices spanning many genes.

Additionally, GWAS often have association signals spanning many genes, which results in several potential gene candidates that cannot be narrowed down using GWAS alone.

Notably, these structural genome variants spanned many genes.

These groups of associated SNPs often span many genes on a chromosome, and once a genetic association is confirmed the task is to investigate how these variants and the genes they are located in contribute to the biological mechanisms underlying disease development.

In this study, we examined the genome-wide recombination that arose when competent H. influenzae cells were incubated with DNA from a diverged clinical isolate, finding that the average cell's daughters replaced ~1% of their chromosomes in multiple independent recombination events that spanned many genes.

Although recombination tracts are limited by the size distribution of donor DNA fragments, they can span many genes and typically include regions of both high and low nucleotide divergence between donor and recipient (Croucher et al. 2012; Lin et al. 2009; Mell et al. 2011).

Such Japanese depictions include numerous dramatizations, spanning many genres.

Some of these span many genes, but the 2p16.3, 7q36 and 16p13.2 loci specifically implicate individual genes (NRXN1, which encodes a synaptic adhesion protein, VIPR2, which encodes a neuropeptide receptor, and C16orf72, respectively) [ 23- 25].

Given that the CNVs under consideration span many genes, both Reviewers 1 and 2 suggested targeted complementation experiments in the deletion and/or duplication cells via recombinant expression and/or siRNA-based methods, respectively.