Consistent with the hypothesis, clofibrate, bezafibrate, and fenofibrate failed to extend nematodal life span in absence of NHR-49 (Fig. 4A and 4B).
Early concepts of RNA as a scaffold for Mg2+-ion catalysts have evolved to a continuum of metal-ion participation in RNA catalysis, with active sites showing a range of interactions that span an absence of direct metal-ion interactions to precisely positioned clusters of three or more specific cations.
The Red Wings have won 7 of 10, scoring 46 goals over that span despite the absence of nine injured regulars.
To a large extent, mouse models of retinal disease recapitulate the human disease, albeit at a different time course and with limitations that stem from the differences between the two species, such as life span and absence of a cone-rich macular region in mice.
Application of this method to cancer research is still in its earliest stages and it will be still necessary to develop better conditions to extend the life span of PCLS in the absence of growth factors and hormones.
A more recent study used conditional gene targeting to ablate B lymphopoiesis in the BM in order to determine the life span of B cells in the absence of B cell influx from the BM.
Elevated practically to the status of a fine art, erasure in our time inhabits many forms, yet spans the same echo-trajectory: the presence of absence, equally haunting and mundane.
By day 14 upon arrest of Fc-BAFF treatmatureature B cell numbers in the blood dropped by 50%, indicating that the life span of mature B cells in the absence of BAFF is 14 days or less.
I am not certain that this is a matter of American self-absorption, but it is certainly indicative of fleeting attention spans and an absence of moral seriousness.
In this case, unit size is small and span of control is low despite a relative absence of direct supervision.
Briefly, tumor response was graded within one of five TRG categories, spanning from the absence of residual tumor cells in the resected specimen (pathologic complete response; TRG 1) to the lack of morphologic signs of tissue response to treatment (TRG 5) [ 10].
