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The implanted tumors have characteristics that are closer to those of human glioblastomas with the C6 cells growing in the intracerebral, intraventricular and intraparenchymal spaces (data not shown).
The gradual appearance of myelinated axons over time along with the absence of myelin debris in extracellular spaces (data not shown) suggests that active demyelination was not occurring.
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This resulted in significant pulmonary infiltration and PMN recruitment into the alveolar space (data not shown) and an approximate 20% mortality.
Bacteria were detected in cells of the meninges (Fig. 2B, right panel, arrowheads) and in the subarachnoid space (data not shown).
In comparison, hearts from 6-months-old spontaneously hypertensive rats (SHR) displayed a pronounced hypertrophy and fibrosis accompanied by high CTGF upregulation with a similar localization in the interstitial space (data not shown).
TbARG crystallizes as a hexamer in both H32 and P321 space groups, but as a trimer in space group P3 (data not shown).
Initially a solution was found in a crystal that crystallized in space group P63 (data not shown).
Greater levels of disorder localize the peaks still more precisely and result in spectra with uneven spacing between peaks (data not shown).
Finally, an analysis of P. ovale infection identified no significant space-time clusters (data not shown).
In our experiment, the detached and pelleted cells were also tested for DAB staining and EM sample preparation, and uninterpretable staining was found at the mitochondrial intermembrane space and endosome matrix (data not shown).
We observed that more pupae died in space than on ground (data not shown) and so it is possible that larvae with poor immunity did not survive metamorphosis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com