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Insight into the effect of spacer characteristics can be obtained by computational fluid dynamics.
They include the types of functional groups and their topological presentation to optimize the bimolecular binding as well as the optimal spatial clustering and spacer characteristics to exploit cooperativity.
Here, a detailed geometric and conformational analysis of 15 glycodendrimers and glycoclusters has been accomplished, which differ with regard to their core moieties, spacer characteristics and the type of terminal carbohydrate units.
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Despite progress made in designing SWM modules in recent years, key issues related to feed-spacer characteristics (particularly spacer material properties in conjunction with their geometry), which affect module performance and membrane integrity, have been neglected by the research community.
The geometric design parameters of spiral-wound membrane (SWM) elements include retentate- and permeate-spacer characteristics and number of membrane envelopes (or sheet width) for constant total membrane area.
The spiral-wound membrane (SWM) element design variables include retentate- and permeate-spacer characteristics and number of membrane envelopes (or sheet width) for constant total area, in addition to membrane surface properties.
By spoligotyping, two isolates from one household (Table 1, IC9 and HC9) had the Beijing genotype and 17 (58.6%) of isolates from nine households lacked eight spacers characteristic of the Manila family [ 12].
The distribution of all key process parameters (at both flow compartments, throughout the membrane envelop) can be predicted, as a function of the membrane sheet and the spacers geometrical characteristics; thus the new simulator is most appropriate for module design optimization, parametric studies and other applications.
Engineering of feed spacers with novel characteristics is an attractive option for reducing fouling within the module, for instance by increasing surface shear forces.
In contrast, S. pyogenes spacer structure was characteristic in that the spacers were variable between strains and the most conserved spacers were observed in only closely related strains (Fig. 2A, B).
b4', the characteristic spacer of mediaevalis cluster Cb4', has only one nucleotide difference with spacer b4 (Table 1), which might indicate a close relationship between Cb4 and Cb4' strains.
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