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To directly confirm ICG extravasation into the interstitial space, we performed immunohistochemical analysis of tumour sections.
In each space we performed tests on datasets with different signal to noise ratios (Figure 1 Panel C).
Once demonstrated that Dil-Ac-LDL+ cells dispersed in the matrigel biopolymer derived from the muscular interstitial space, we performed a similar experiment, injecting only matrigel loaded with VEGF without the previous intramuscular Dil injection.
In sensor space, we performed t-tests for every point (voxel) in the 3-dimensional space defined by the 2-dimensional MEG sensor-space projections and time.
To validate the characteristics of the transformation of spurious and phenotypic vectors in Clinical Face Phenotype Space, we performed a series of experiments based on projected 3D faces.
Because the sampling procedure is a linear one and because we sought a basis for the sampled space, we performed Principal Components Analysis using Singular Value Decomposition.
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Every space we perform in is so different – the Linbury Studio at the Royal Opera House is very intimate, while in Malvern, the audience feels quite far away – so I scan through the auditorium and all the seats, to make sure I connect to everyone, through to the person right at the back.
In order to optimize the search space, we perform a series of docking calculations for each target using a cubic box whose edge lengths range from 2 to 36 Å with a small incremental step size of 2 Å to ensure a fine-grained sampling.
To reduce the parameter spaces, we performed an iterative two-mode process of model "creation" and "testing"; "Creation" is to develop and fit our model with published available semi-quantitative profiles of NF-κB and MAP kinases activity in wildtype (step 4).
To directly test the hypothesis that reciprocal binding of HMGD1 and H1 has functional consequences for gene regulation and nucleosome spacing, we performed siRNA knockdown of both HMGD1 and H1 [ 31, 50].
Under satisfactory general anesthesia with the patient in a left lateral position, thoracotomy was performed through the fourth intercostal space, and we performed subtotal esophagectomy with lymph node dissection.
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