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This is the fastest biotransformation process ever reported for INA production with time and space productivity of 36 g L-1 h-1 using a bacterial nitrilase.
This puts retailers under pressure to manage profitability with narrow margins and to maintain space productivity (Gutgeld et al. 2009).
The biotransformation process developed using N. globerula NHB-2 nitrilase achieved the time and space productivity of 36 g L-1 h-1 INA which is almost 38 times higher than above reports.
Reaction was carried out at 35°C and 100 mM 4-cyanopyridine was fed at an interval of 20 min. The time and space productivity of any bioprocess is its key feature, ruling the feasibility of its commercialization.
N. globerula NHB-2 nitrilase achieved the time and space productivity of 36 g L-1 h-1 INA which is almost 38 times higher than the above processes.
In CSMRs cascade loaded with nitrilase (6.5 U) and amidase (5 U) as cell-free extracts immobilized in CLEAs produced 3.36 g INA (99.9%) in 52 h with the time and space productivity of 118 mg L-1 h-1 when 50 mM 4-CP was pumped at the rate of 10.5 mL h-1 (Malandra et al. [2009]).
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IDoneThis CEO Walter Chen holds that his product is in the same space as productivity tools Rypple and Yammer, and that users are loving it.
In terms of time and space, the productivity of INA (36 h L-1 h-1) reported here is the highest.
Users can add up to six 940UX monitors on one PC, providing up to 114 inches of desktop space increasing productivity by giving users the ability to have multiple windows open across multiple displays".
Everywhere the logics of funding, production and capitalization are more intertwined than ever, redefining asymmetries through spaces and productivity hierarchies.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com