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A fraction of SP in control Neo cells ranged from 0.175% to 0.28% of the whole assessed cell population, whereas the number of SP cells was significantly increased in cells overexpressing hHSF1 (>2 fold: an effect especially well noticed in B16F10 line) compared to control cells.
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CCNG2 expression was significantly lower in Panc1-P (Sp) than in control.
However, to date, the regulatory role of SP in the control of melanogenesis has not been elucidated.
The drugs used were SP+PQ in one intervention village and SP in one control village.
Regarding the differences in tumour burdens between SP- and non-SP-inoculated mice, tumour burden in SP control mice was greater (92.3%) than that in the non-SP control group.
There were no significant apoptotic cells in control SP and verapamil-treated SP cells.
However, mir-278D ko females showed a nonsignificant tendency for weaker responses to SP in comparison to controls.
By contrast, SP-D was significantly higher in control males as compared to females, and SP-D correlated positively with age.
Total protozoa numbers assessed by microscopic counting were 1.7 and 2.1 times greater in SP and FIL fermenters than in control ones on day 14, although differences did not reach the significance level (P = 0.855).
SP cells were not detected in control (Fig. 5A).
Protozoal DNA concentration on day 14 were 1.6 and 1.4 times greater in SP and FIL fermenters, respectively, than in control ones, but differences were not significant (P = 0.524).
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