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But unlike legal markets, drug buyers have little choice when sourcing substances.
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Considering the vast array of sources, substances, and methods with which food is produced, practically every kind of microbe is a potential contaminant.
DTXRIDs are unique identifiers of source substances, mapping to a substance record from an external source list carrying all source-associated identifiers.
Supporting civil society activities in countries where CSOs are weak or repressed, while personally boycotting illegally sourced substances altogether until goals are achieved, is another.
For the remaining two chemicals, the duplicate Dibutyl phthalate samples had low NR activity and grouped closely in NRG F and NRG G (these samples were separately sourced substances from two different vendors).
We agreed to choose categories for which toxicology studies are available for both target and source substances to facilitate the assessment of whether additional information actually is strengthening the read-across case.
The majority of drugs or their metabolites cross the placental barrier, 5 and metabolites may be more fetotoxic than their source substances, as was noted in the case of thalidomide-induced phocomelias.
The source substance powders were mixed in the same proportions and treated in cycles (the cycle time was 5 min) in the planetary-type ball mill (acceleration 50g, pressure on a substance particle 5 GPa).
The list curation process to fully register a list in DSSTox involves not only initial mapping of source IDs to DTXSIDs, where possible, but also identification of "No Hits" and delineation of partial or tentative source-substance ID agreement.
The DSSTox Chemical Property database (DSSTox-ChemProp) was built as an add-on to DSSTox-Lists to capture measured or predicted property data associated with a particular source substance or list of chemicals (DTXRIDs).
Despite its open-source substance, it's hefty: Three meters tall, four meters in diameter.
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