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"All avenues of research should be exhaustively investigated, including both adult and embryonic sources of tissue," the report says.
At another point, Giroir said that any alternative sources of tissue "must be as predictive, as reliable and as validated as existing models" that use fetal tissue, according to another participant, Mike McCune, a longtime HIV researcher who is a senior adviser to the Bill and Melinda Gates Foundation.
We hypothesized that (1) MSCs would increase survival and mesenteric perfusion, preserve intestinal histologic architecture, and limit inflammation after intestinal ischemia and reperfusion (I/R) injury, and (2) MSCs harvested from different sources of tissue would have equivalent protective properties to the intestine after I/R inury.
CONCLUSIONS: These observations demonstrate that significant sources of tissue ACE in human atherosclerotic plaques are regions of inflammatory cells, especially areas of clustered macrophages as well as microvessel endothelial cells.
Extrapancreatic tissues such as liver may serve as potential sources of tissue for generating insulin-producing cells.
We used two independent sources of tissue arrays to obtain a bona fide expression profile independent of the individuals analyzed and the type and method of preparation of the microarrays.
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Cluster analysis suggests that fertilizers and other agrochemicals, are likely sources of tissues contamination in species foraging on soil invertebrates.
A challenge in urologic tissue engineering is to obtain well-differentiated urothelium to overcome the complications related to other sources of tissues used in ureteral and urethral substitution.
Since the discovery of mtDNA methylation way back in 1977 in animals (Vanyushin & Kirnos, 1977), quantitative and qualitative analyses of mtDNA 5-methylcytosine (5mC) of human from three different sources of tissues viz.
Human embryonic stem cells (hESC) are currently being developed as sources of tissue-specific cells for the treatment of human disease, including heart failure.
It is quantitative, it overcomes the technical difficulties that plague telomere length measurements and is applicable in all types and sources of tissues, importantly including cryopreserved banked specimens (Horvath, 2013).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com