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The increase in serum protein content might be in part due to an increase in the WBC number, which is a major source of serum protein production such as immunoglobulin, lysozyme, complement factors and bactericidal peptides (Misra et al. 2006a, b).
The results varied directly with the source of serum used for generating and maintaining NB.
The fuzzy concentric pattern was independent of the source of serum or the type of serum treatment used.
Since the liver is thought to be the major source of serum GGT activity [18], we speculate that the liver and blood levels of GGT1 mRNA may be coordinately regulated.
Since both the cellular source of serum TRAIL and the mechanisms of secretion of soluble TRAIL are incompletely understood phenomena [7], [24], it is unclear whether the significant decline in the serum levels of TRAIL reflects a deficit of production or an increased consumption of TRAIL in the acute phase after AMI.
Although the cellular source of serum TRAIL has not been clearly established, it is important to point out that TRAIL is expressed as a type-II TNF family transmembrane protein, but its extracellular domain can be released as a soluble cytokine [7].
Similar(23)
The effects of serum on NLP formation could be analyzed in a similar manner, as done initially with NB, using different amounts as well as sources of serum.
The tissue sources of serum amidating activity have not yet been identified.
Since the major tissue sources of serum PHM and PAL remain unknown, it is difficult to interpret this unexpected result.
Given that there are various sources of serum chemokines, other than those produced by peripheral blood leucocytes, measurement of the mRNA levels of these chemokines in peripheral blood cells is possibly a direct indicator of the dysregulation of chemokine expression that exists in peripheral immune cells in patients with SLE.
The source(s) of serum MMPs probably includes circulating leucocytes, especially neutrophils and monocytes, whereas the contribution from the tissues is uncertain.
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