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It seems that the spectral overlapping and similarity of some surface features were the source of misclassification in accuracy assessment.
Patients with different clinical phenotypes have been diagnosed as having migraine, and even strict classification according to IHS criteria [15, 16] may not sufficiently capture this variability and may be a source of misclassification in all studies.
We included only studies that reported laboratory-confirmed estimates and excluded those providing clinical diagnoses alone, removing a potential source of misclassification bias.
However, because potential probes are first screened for non-unique sequence, and probes with too many genomic matches discarded, this is likely a small source of misclassification.
Thus, our data may underestimate the extent of RWP support for care, but unless receiving ADAP impacted the care outcomes we analyzed, this should not represent a source of misclassification bias with respect to our primary conclusions.
However, for future studies, the erroneous assumption of linkage for one quarter of identified transmission events could clearly be a major source of misclassification bias with a consequent high risk of inaccurate conclusions about risk factors for HIV-1 transmission or efficacy of interventions to reduce HIV-1 infectiousness.
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These findings will have a broad interest to ecologists wishing to account for multiple sources of misclassification error in capture-mark-recapture studies, with the caveat that the specifics of the approach are dependent on species, transmitter types and other aspects of experimental design which may or may not be amenable to the misclassification framework.
There are other potential sources of misclassification.
In addition, we identify current sources of misclassification that limit algorithm performance.
An analysis of errors revealed sources of misclassification in terms of both missed seizures and false detections.
However, we have no reason to believe that any of these potential sources of misclassification were differential in nature.
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