Sentence examples for source of methyl from inspiring English sources

The demand for de novo phosphatidylcholine synthesis, however, is complex and depends on the dietary supply of preformed choline, the demand for choline as a source of methyl groups for methylation of homocysteine, and the needs of phosphatidylcholine and sphingomyelin for membrane, bile, and plasma phospholipid synthesis and turnover.

SAM then serves as a source of methyl groups for multiple methylation reactions, including the methylation of DNA.

Folate plays a crucial role as a methyl group donor, contributing to the cellular supply of S-adenosylmethionine (SAM), the proximate source of methyl groups for DNA methylation.

This outcome is contrary to the expected given the MTX suppression of SAM [ 38], which is the major source of methyl groups for DNA methylation.

Dietary folate (from green leaves) is the main source of methyl group necessary for DNA synthesis and DNA methylation.

Using S-adenosylmethionine (SAM) as the most common electrophilic source of methyl groups, various methyltransferases modify DNA, RNA, and proteins to generate different biological methylations that impact gene expression regulation.

Given the role of aberrant DNA methylation profiles in cancer, the potential of methyl-donor diets to modulate miR-21 levels is particularly interesting, especially since methyl-donor nutrients are the major source of methyl-groups in one-carbon metabolism cycles, and therefore influence the availability of methyl-groups for use in biological processes, including DNA methylation [30], [31], [32].

We also did not have a measure of plasma choline or betaine, which may both be relevant sources of methyl groups for As methylation.

The onset of lactation in dairy cows is characterized by high output of methylated compounds in milk when sources of methyl group are in short supply.

That view is strongly disputed by many atmospheric chemists, who say that while human sources of methyl bromide are less significant than was once thought, they remain a significant destroyer of ozone.

Under such a condition, without additional sources of methyl groups including methionine, which further metabolizes into homocysteine and cysteine, methyl donor deficiency results in poor milk protein or yield performance (Scott 1999; Abbasi et al. 2018).