To identify the sources of lack of agreement, discrepancies between the medical record and the HHQ were assessed.
Two well-known sources of lack of replicability are reduced statistical power due to small (and varying) experimental samples sizes [ 5, 9, 10]; and population stratification [ 11].
The CV for based on LD is (Hill 1981; Waples and Do 2010): (5) where n is: (6) The CV provides a theoretical insight on other potential sources of lack of precision of the estimator: number of alleles and sample size are also expected to influence the precision of the estimator and most previous simulation studies of equilibrium report behaviours in line with theory.
Other potential sources of lack of replicability include disease heterogeneity, since some complex diseases might include similar entities with shared symptoms but different genetic architectures [ 12]; hidden age-varying effects [ 13]; biased ascertainment of genetic markers [ 14] and publication bias [ 7].
The precise extent of depth of field is somewhat subjective because focus drops off gradually from the precise distance of focus, and the noticeability of defocus depends on factors such as subject type, other sources of lack of sharpness, and viewing conditions.
Possible reasons why more eligible women do not receive cervical cancer screening include fear of painful procedures, fear of having cancer, lack of insurance, high deductibles and co-payments, lack of a usual source of care, lack of knowledge about screening or recommended screening intervals, lack of transportation, and lack of nearby providers [ 10, 15, 23– 28].
However, different source-apportionment methods usually produce similar main sources, although, for example, traffic is a more difficult source because of lack of unique elemental tracers (Thurston et al. 2005).
The main barrier reported when prescribing in pregnancy was access to current information about medication effects on the foetus, due to lack of a single comprehensive source of information, lack of time to access information and rapidly outdated information [ 20].
Morgan et al. found that the major barriers to prescribing during pregnancy were lack of a single comprehensive source of information, lack of time and the fact that information gets outdated rapidly [ 23].
Modification indices were used as indicators to explore the sources of lack-of-fit.
