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Recently, the accelerated pace and sophistication of methods for structural characterization of proteins has allowed high-resolution studies of increasingly complex assemblies and conformational changes.
The sophistication of methods used is influenced by three factors.
While calculating the costs of DEXA, CT, and MRI solely by the actual amount of time spent scanning makes these techniques comparable, the total costs remain significantly different because of the time and sophistication of methods needed to analyze the acquired data (Table 1).
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In general, the methodological quality of empirical papers on IC in healthcare was poor, largely for two reasons: inadequate description of the methods and limited rigor and sophistication of the methods.
Actually, these in silico predictions have not raised a lot of orphan cases despite the sophistication of the methods and their relative independence from classical sequence based methods.
Compared with the wealth and sophistication of imaging methods available for patients with MM, the sole reliance here on one method, FDG-PET, is a reminder that preclinical imaging of PCT in mice is in its infancy.
Apart from the greater sophistication of modern methods of heating and the use of resin (or oil for use on canvas), present-day technique is similar to that described by the 1st-century-ad Roman scholar Pliny the Elder.
And the sophistication of attack methods is only increasing and becoming more difficult to detect.
Things continue to move fast on both sides of the equation, with both black hats and white hats evolving the sophistication of their methods and tools.
This is an important set of analyses and inferences partly because of the sophistication of the methods employed, as well as the amount of genetic data used to model the "pause" and subsequent colonization.
Radicalization to violent extremist agendas is a growing challenge among this demographic in Bangladesh; and one of the reasons is a lack of suitable job opportunities (additional drivers include a disassociation from traditional values and the sophistication of recruitment methods in some Universities, among others).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com