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Far from providing small, unsigned artists with the means to bypass major labels, the tale of Sandi Thom suggests that major labels have swapped their early panic over internet piracy for a sophistication in using it to promote new artists that has overtaken the media's ability to sniff out a PR stunt.
However it is important not to underestimate the additional planning and commitment needed if further sophistication in using technology to support clinical education is desired (for example, online simulation or assessment).
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The increasing sophistication in making knockouts using TALENS [ 49,49] and the Cas9/CRISPr [ 50] genome editing system has made it possible to target nearly any candidate cancer gene in the in vivo setting.
After some training in flint knapping, he created and used the tools to break apart logs and dig out concealed food – the first time this level of technological sophistication in tool use has been observed in non-humans.
The marked acceleration in technological developments and sophistication in their use have resulted in new techniques for the planning, commission, and concealment of criminal activities.
Both have also shown savvy and sophistication in the use of social media and the recruitment of jihadist volunteers among diaspora Muslims born and raised, in many cases, in the U.S. or Western Europe.
And there has never previously been anything remotely on the same scale as IS in terms of financial resources, number of fighters, territory controlled, sophistication in its use of media and ability to radicalise young Muslims in the West.
Her work, Breuer's, and that of many other artists active in the field today, are testament to a growing sophistication in the use of puppetry forms on the American stage.
A playful West joins Pharrell on "Number One," a piece of orchestral hip-hop with a sweet sentiment and Steely Dan sophistication in its use of backing vocal choruses.
"Striking Iron" is a large and absorbing exhibition, apparently the first of its kind to survey the importance of the material and the sophistication in its uses on the continent, mostly in regions south of the Sahara Desert.
Plant genetics has a long and distinguished history of using Occam's broom [see the "process of sophistication" probably used in the collection of Mendel's data (Fisher 1936 ], and it is routinely used in mapping algorithms even today.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com