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In the case of evolutionary transitions, this allows us to separate the basic development involved in the origin of a new biological level from the later evolution of sophisticated developmental mechanisms for the "stabilization and maintenance of a new level of reproduction" (2000, 77).
These programs require the generation, according to sophisticated developmental pathways, of a set of specialized cell types.
This sophisticated developmental program requires regulation of gene expression and protein synthesis [ 6, 7].
FoxP3 plays a key role in a sophisticated developmental program that nudges the immature T cell lineage into a regulatory pathway during positive selection on high affinity T cell receptor ligands [ 4].
This is especially so in an era of increasingly sophisticated developmental genetic analysis, as the correct interpretation of molecular data depends largely on the precise characterization of morphological structures (e.g., Prud'homme et al., 2011 vs Yoshizawa, 2011; Mikó et al., 2012).
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The mammary gland undergoes a sophisticated programme of developmental changes during pregnancy/lactation.
The red flour beetle, Tribolium castaneum, is a highly sophisticated genetic and developmental model organism [ 19], and is a major global pest of stored agricultural products.
In particular, they lie at a deeper, autonomous level of spiritual life which then gives rise to the more sophisticated forms by a dialectical developmental process.
A variety of sophisticated statistical techniques (e.g., developmental trajectories), which will allow systematic research on several key electrophysiological measures, will be useful to highlight longitudinal aspects of cognitive development as well as the nature and course of the disorder under investigation.
From the pioneering work using zinc-finger nucleases (ZFNs), to the advent of the versatile and specific TALEN systems, and most recently the highly accessible CRISPR/Cas9 systems, we now possess an unprecedented ability to analyze developmental processes using sophisticated designer genetic tools.
Moreover, there is increasing evidence that quite sophisticated cognitive abilities are available at developmental stages much earlier than had been previously believed (Bransford et al. 2000a, b; Siegler 2005).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com