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The rapid emergence of computational social science has thrust sophisticated computational methods into the sociological mainstream.
We plan to maintain KampoDB by updating the molecular data on a regular basis and by analyzing the data using more sophisticated computational methods.
Today's drug designer has access to vast quantities of data and an impressive array of sophisticated computational methods.
Sophisticated computational methods have recently led to impressive progress in this exciting and rapidly evolving field (Röthlisberger et al., 2008; Jiang et al., 2008).
It is expected that further studies in addition to these methods will be utilized for in silico RNA aptamer design, permitting a minimal number of experiments to be performed through the utilization of sophisticated computational methods.
High-throughput technologies such as mass spectrometry produce large amounts of data that require sophisticated computational methods to preprocess and identify highly discriminatory features (biomarker candidates) from these data.
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However, the challenge can be defeat by forming mathematical descriptor to represent the histologic texture and classify the structural changes via a sophisticated computational method.
At the intersection of classical automation and more sophisticated computational intelligence (CI) methods, there is a huge potential to develop intelligent automation systems.
As a general conclusion, the interplay between new and more sophisticated engineering protocols and computational methods, based on molecular dynamics simulations with Quantum Mechanics/Molecular Mechanics potentials and fully flexible models, seems to constitute the bed rock for present and future successful design strategies.
Successful application of physics-based protein-structure prediction methods depends on sophisticated computational approaches to global optimization of the conformational energy of a polypeptide chain.
Just as the vast sequence data available for the human [ 1, 2] and additional organisms [ 3- 5] require sophisticated genomic browsing tools [ 6- 8], computational methods are required to thoroughly explore the corpus of biomedical literature.
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