The panel, which included statistician David Hand of the Imperial College London, concluded that outdated statistical methods had been used as a result, although panel members didn't think that more sophisticated methods would have altered the researchers' conclusions.
At that stage, more sophisticated techniques that alter the original properties of the reservoir are used.
Immunomodulation in infectious diseases, cancer, cardiovascular disease and autoimmunity can now be targeted by sophisticated protein design, altering cellular responses by increasing therapeutic cell numbers ex vivo and then reimplanting, or altering cell function by gene transfer of cells ex vivo.
It was also found that the rheology and stability of the cement slurry will not be altered if a sophisticated dispersion technique is employed (de Paula et al. 2014).
Whereas some studies implement sophisticated modeling systems to estimate altered air quality, capturing regional differences in pollutant levels [ 13], others use simple target values with uniform pollution reductions across all spatial areas [ 12].
Deciphering mechanisms of muscle weakness requires sophisticated force protocols, dissecting contributions from altered Ca2+ homeostasis, electro-chemical, chemico-mechanical biosensors or visco-elastic components.
For submerged terrestrial plants, O2 deficiency and escape responses via shoot elongation have been elucidated, revealing sophisticated signalling, changes in gene expression and altered metabolism during submergence (e.g. reviewed by Bailey-Serres and Voesenek 2008, 2010).
Using the Sega Saturn and PlayStation's advanced hardware, many elements of the original game's presentation have been altered, including a larger color palette, more sophisticated visual effects, and improved sound quality.
More sophisticated laboratory analysis, especially DNA typing, has also altered how the shield laws work.
One of the most sophisticated houses on Carnegie Hill, this brownstone was first altered by Roswell Barratt for Caramai and John Taylor Johnston Mali in 1931.
