Sentence examples for sonic hedgehog from inspiring English sources
noun
A morphogenic protein that controls cell division of adult stem cells and has been implicated in the development of some cancers.
No time exposed to sonic hedgehog turns them into thumbs.
But inspection of the Sonic hedgehog genes of polydactyl individuals did not reveal any mutations that would cause the Sonic hedgehog signal to be defective.
The induction of polydactyly by Sonic hedgehog in laboratory experiments raised the possibility that inherited cases of polydactyly might be caused by mutations in the Sonic hedgehog gene.
These signals are themselves proteins, like the highly important Sonic hedgehog.
As their supply of sonic hedgehog drops, the cells cannot make gremlin proteins.
Cells that produce sonic hedgehog are exposed to the protein the longest.
Meanwhile, cells near what will become the pinky start making sonic hedgehog.
So by keeping BMP4 levels low, sonic hedgehog lets the ridge continue to function.
Without the ridge's help, the limb bud can no longer make sonic hedgehog.
They then found that the Sonic hedgehog protein was indeed the long-sought digit-patterning signal.
