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As observed in a product complex, the lactonase's active site appears to somewhat tighten around the bound ligand, although not around the hydrophobic acyl chain (16).
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In fact, this change brings the two sets of values in somewhat closer correspondence and slightly tightens our estimate for the range of possible values of the pEndos dephosphorylation K m.
With over half the vote in and Clinton leading by 16 points, the networks are calling it for Clinton - though as Richard points out below, with most of the major cities still not counted, that margin could tighten somewhat and affect the delegate apportionment.
Things did tighten up somewhat once he moved into City Hall — everything but the mayor's need for making news, for approval and for attention.
The Federal Aviation Administration has, somewhat clumsily, been tightening up various cabin safety procedures.
The results do seem have tightened somewhat since the first debate, which Romney was widely seen to have won, right?
The Fed reported that 14 of 22 foreign-based banks operating in the United States "tightened somewhat" over the last three months, while one had "tightened considerably".
"Without a doubt unsecured U.S. dollar funding markets have tightened somewhat recently," Andreas Dombret, a member of the executive board of the Bundesbank, Germany's central bank, acknowledged Wednesday.
Although the rules have tightened somewhat again under President Mahmoud Ahmadinejad, Iranians have responded as they often do — occasionally breaking the rules in private.
The day before, the Security Council had tightened somewhat its mild arms embargo on the Sudanese government and imposed sanctions on as-yet unnamed individuals impeding the peace process in Darfur.
The survey found that 28 of the 57 banks surveyed had "tightened somewhat" the availability of loans to large and midsize companies with sales of at least $50 million a year.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com