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When a new drug is marketed, side effects are virtually inevitable, and they are sometimes more severe or more common than when the drug was being tested.
Overall, the results showed that Hg accumulation from intermittent exposure was less than that of the continuous exposure regime, but the sub-lethal responses are sometimes more severe than expected in the former.
I have battled depression for as long as I can remember -- sometimes mild, sometimes more severe -- and have successfully used service to cope with the sometimes debilitating effects of depression.
Patients also report that fatigue is interwoven, influenced, and intensified by pain, and is sometimes more severe than pain [ 18].
Nearly all of these patients have some sort of cortical malformation; most have perisylvian polymicrogyria, but the polymicrogyria may be more widely scattered and is sometimes more severe over the convexities.
The symptoms associated with campylobacteriosis range from mild enteritis with or without bloody diarrhea, fever, abdominal pain to severe invasive diseases, and are sometimes more severe than Salmonella and Shigella infections [ 10].
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Adverse reactions to an antidepressant rechallenge are not uncommon [ 150] and sometimes a more severe antidepressant-induced hepatotoxic reaction may occur following antidepressant rechallenge [ 139, 153].
Growth of females with MTD-Gal4-driven shRNAs at 29° sometimes produces more severe phenotypes and more effective knockdown of the target mRNA (Ni et al. 2011; this study).
Persistent asthma is often treated with inhaled corticosteroids (ICS) in combination with short acting beta agonists (SABA) as needed, or sometimes in more severe cases, long acting beta agonists and/or leukotriene antagonists [ 3].
Many families learn of problems this way, as routine ultrasounds uncover abnormalities like extra digits, club feet or cleft palates that sometimes signal far more severe problems, said Dr. Suzanne Toce, medical director of the Neonatal Intensive Care Unit at Gundersen Lutheran Health System in La Crosse, Wis., and director of a hospice program.
However, surface modification can significantly change the membrane filtration properties, sometimes resulting in more severe fouling than with the original, unmodified membrane.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com