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Since nonfunctionality of pseudogenes is sometimes difficult to define, Zheng and Gerstein [ 10] proposed a classification system of genes and pseudogenes.
However, transgenic labeling of neuronal subpopulations in vertebrates has proven to be complicated, as cis-regulatory elements (e.g., promoters, enhancers) that delineate specific neuronal subtypes are sometimes difficult to define.
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Heading west, these likeminded pioneers traded paintbrushes for heavy machinery, creating gashes in the ground, erecting structures and manipulating the very landscape toward their own sometimes difficult-to-define goals.
In the well-established population balance many kinetic coefficients appear which are sometimes difficult to determine.
However, clinical relevance of sensitizations is sometimes difficult to determine.
Possible communication with the joint is sometimes more difficult to define than on ultrasound and MRI.
Sometimes it is difficult to define the latter mark, because it varies with the skin transparency of various subjects [ 66].
Health care is a wide area, and sometimes it is difficult to define which actions belong to it and which, for example, to social security.
The midwives described how sometimes they found it difficult to define and discuss violence in the care encounter, particularly psychological and economical violence, due to possible divergent roles and relations within families.
As indicated in a previous study, the B clade is much more difficult to define and is sometimes composed of sequences that do not fall into D or E clades [24].
The seasonality of malaria transmission for a given setting was difficult to define, with contradictory descriptions sometimes given by different authors for the same site.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com