"Some previous trials of supplements showed benefits," Dr. Mozaffarian said.
Here is a look back at some previous trials of dictators, autocrats, and other absolute rulers, with a focus on the elements of theatre and closure — which often never comes.
However, contrary to some previous trials about CR in bipolar disorder (Deckersbach et al. 2010; Torrent et al. 2013), we could not confirm our hypotheses that psychosocial functioning and life quality improve by a cognitive rehabilitation program.
Although the current results are consistent with some previous trials showing genistein exerts skeletal benefits, there are important differences.
Pooling our data also allowed for a large sample size and sufficient power, which was a limitation of some previous trials.
The only difference between this trial and some previous trials [ 11, 12] was that in our study patients who had triple dependence (opioids, benzodiazepines and alcohol) and those who could not be contacted by phone were excluded.
The mean effects of the SE program were less relevant than those reported in some previous trials [ 39, 40], but are in line with those obtained in some other recent studies [ 12, 41].
However, the reluctance of caregivers and health care providers to carry out the cumbersome stool collection experienced by us when conducting some previous trials was the main reason for not including stool output in this study's protocol.
Some previous trials have used the average of the uninjured subjects bilateral values as a comparison, however this was unsuitable in this trial due to the higher strength of the dominant limbs, and the higher proportion of dominant limbs in the injured group.
The Hokusai-VTE study of edoxaban is the most recent study and aimed to address some weaknesses of previous trial designs.
A previous trial ended in a hung jury.
