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After functional annotation, we found some pathways which could be biologically related to carcass weight, e.g., actin filament processes and TGF beta-activated receptor activity.
Moreover, extrapolating findings in lower model organisms to more complex organisms, such as humans, bears the inherent risk that some pathways, which are less important or absent there, may be overlooked.
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(3) Some miRNAs down regulate cancer hallmarks by downregulating some oncogenic pathways, which was also inferred by other studies [74].
Some physiological pathways which differed in D relative to Wa, but not Ws, were homeostasis, protein metabolism, translation and apoptosis.
Presence of several new activation loop motifs in plants may be responsible for some novel pathways which are yet to be elucidated.
However, both of these diseases may share some pathophysiological pathways, which may be mediated by the hypoxia inducible factor family (HIF) [ 61].
The DNA microarray approach has pinpointed some metabolic pathways, which are differentially regulated by phagocytosis and/or growth on bacteria, and has led to identification of several interesting genes, some encoding signal transducers, transcription factors, membrane receptors and other hypothetical membrane proteins.
Among them, we found some genes and pathways which may be related the abnormal phenotype.
These findings could be implicative of some important molecular pathways, which may or may not have been identified, that drive the development of ovarian cancer.
The constructed Bayesian network has identified some new genetic/epigenetic pathways, which may shed new light into the molecular mechanisms of ovarian cancer.
FTC and PTC share some characteristics –genes and pathways– which are related to DNA damage repair or cell cycle arrest.
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CEO of Professional Science Editing for Scientists @ prosciediting.com