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However, some normal physiological conditions can be misdiagnosed for false lung points [30, 31].
In some normal physiological circumstances, and in some cell types, there is a predominance of one isoform.
Next step, people will be interested in profiling the temporal and special gene expression patterns in the individual human organs or cells on a genome-wide scale and comparing with some normal physiological processes and diseases status as well.
This result indicated that both NATs and GC tissues lose some normal physiological functions, with the alteration in the expression of barrier function-related genes being more frequent in NATs, followed by the alteration in the expression of secretion-related genes in the GC tissues.
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Although some of the normal physiological actions mediated by 5-HT7 such as anti-proliferation and pro-apoptosis would inhibit tumor progression, it is not a simple matter that 5-HT7 is uniformly tumor-suppressing.
To date, numerous genes have been identified which are involved in both tumour neovascularisation (angiogenesis) and tumour cell invasion, and most of them are also expressed to some extent under normal physiological conditions.
Thus, some but not all normal physiological functions are altered by this strong environmental factor.
The apparently large extent of somatic mosaicism suggests, however, that some mutations may have normal physiological functions [ 4].
Numerous studies have indicated that the presence and modulation of EMMPRIN might play some role in the normal physiological processes (Gabison et al, 2005a, 2005b).
The standard CD44 (CD44s) isoform is present on the membranes of most vertebrate cells and alternative splicing generates several variants (CD44ν) are only expressed on some epithelial cells in normal physiological conditions [ 17].
Under normal physiological conditions some 15 percent of the glomerular filtrate is reabsorbed in the distal tubule.
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