Furthermore, some of the mentioned studies referred to the same patient population [ 22, 24, 26].
In our meta-analysis, we did not include some of the mentioned studies because of the following reasons.
In some of the mentioned studies, optimal yields of aromatics were obtained by application of two-phase systems which combine the culture medium with an organic solvent for immediate removal of toxic aromatic products, a technique for which P. putida S12 is especially suited due to its remarkable solvent tolerance (Heipieper et al. 2007, Verhoef et al. 2009).
In contrast to some of the previously mentioned studies which have some minority representation, this study was fully recruited with a diverse patient population.
Also, in some of the above mentioned studies and in others, as in [14], the discretisation is pursued by considering a particular discretisation of the datum f (namely, by using integral averages).
Although accumulation of Hsp70 was measured in some of the above mentioned studies [27], [28], it is not possible to conclude from these data (or from our data presented in Fig. 4G) whether it is the synthesis of Hsps or some other physiological change occurring during heat pretreatment which confers higher cold tolerance on the pretreated individuals.
This was in accordance with some of the above mentioned studies.
The differences seen with some of the previously mentioned studies could also be due to different antibodies used for the immunohistochemical staining.
One weakness with some of the above mentioned studies is the relatively small sample sizes used for the factor analyses since that may influence the result of these analyses.
In the above mentioned studies, some negative ramifications of publication of the data were described, such as selection by hospitals based on risk or a very one-sided view on the easily measurable aspects of quality (in relation to those less accessible to measurement).
Despite mentioned studies and some other conducted experiments in this field (Hernandez et al. 2004; Kavyani et al. 2012; Lee et al. 2012; Toghyani et al. 2012), data on mushroom wastes are scarce.
