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The phrase "some major changes" is grammatically correct and commonly used in written English.
It can be used to describe a group or collection of significant or important changes. Example: The company announced some major changes to their business model, including a shift towards sustainability and a rebranding of their products.
Exact(60)
Global climate change is anticipated to cause some major changes in hydroclimatic conditions around the world.
One division manager wanted to make some major changes in his organization.
Below are some major changes in copyright law that may affect you or your business.
During the last decades the European countryside has witnessed some major changes.
The process of building design is currently undergoing some major changes.
Since then, Malaysia has seen some major changes in its energy and electricity generation scene.
Clearly, some major changes are already flowing from the defection of Senator James Jeffords from the Republican Party.
I hope to make some major changes in the curriculum structure itself as well as the methodology".
Over the really long term, however, the U.S. government will have big problems unless it makes some major changes.
As humans emit greenhouse gases (particularly carbon dioxide), we see some major changes that cannot be explained naturally.
Fastcase's legal research service is poised to make some major changes in the way that lawyers access the law.
More suggestions(15)
some major modifications
some substantial changes
some weighty changes
some momentous changes
some major alterations
some great changes
some fundamental changes
some important changes
some major trends
some large scale changes
some major shift
some broad changes
some major revisions
some serious changes
some big changes
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com