Sentence examples for some loss of expression from inspiring English sources

Thus, while there was some loss of expression signal (expected as fewer contigs are assigned to GRS datasets compared to the CCDS), using the GRS as'gene' grouping proxies was still informative.

They frequently present P53 alterations and WISP3 loss-of-expression [9] [15].

Using non-target species as reference scaffolds does result in some loss of sequence and expression data, and bias and error increase with evolutionary distance.

However, it is of interest that some pools displayed a loss of expression of the exogenous cyclin E with prolonged serial passages that was associated with a decrease in the expression of MnSOD to the normal basal level (data not shown), thus further confirming the link between the two events.

There is immuno-histochemical evidence showing reduced Trask/CDCP1 expression in some cancers and biochemical data showing that a reduction or loss of expression in some cancer cells due to promoter hypermethylation [14], [15].

This is consistent with either a complete loss of expression in some but not all cell populations or a one copy number loss throughout most of the tumor cells since samples are heterogeneous.

In contrast to miR-21, miR-200 family is known as tumor suppressor and they are usually down-regulated in some tumors including PC and the loss of expression of miR-200 family contribute to the acquisition of EMT phenotype and drug resistance.

The lack of obvious phenotypic effects associated with the loss of expression of some Wnt genes in particular tissues suggests that they may be functionally interchangeable in certain contexts [e.g. [ 23, 66]].

Thus, the loss of expression of some of these paracrine factors in RIP140 KO mice probably accounts for the reduction in the number of stem and progenitor cells observed in the mammary glands of these mice.

Some studies have shown that the simultaneous loss of expression of FHIT and WWOX is frequent in several cancers [ 52- 54].

This is also readily apparent in Fig.  4a, because some individuals exhibited reciprocal patterns of gain or loss of expression.