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Some indirect observations are supporting this hypothesis.
Indeed, some indirect observations partially corroborate the proposition: the most recent results of Lu et al. (2009) demonstrate that while 80% of the b2/b3 deletions occurring in fertile normozoospermic men belong to the deletion-fixed haplogroup N, this fraction decreases to ∼65% when considering infertile men.
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The idea that some breast cancers are pre-initiated in utero is supported by several indirect observations in human populations.
Until now, we have only had the crudest information about these other distant worlds – mass, orbit, approximate temperature – mostly gathered from indirect observations of them passing in front of their host star.
Direct measurements vindicated previous indirect observations.
Thus, inferences from indirect observations must be made.
The methodology involved direct and indirect observations along transects as well as focus group discussions.
Indirect observations often lead to ill-posed inverse problems, where the use of prior information plays a crucial role.
He also commented on the use of indirect observations (e.g. taking measurements from machines being used by the workers) to supplement direct observations.
Astronomers also caught one transiting the face of its star, a more direct sighting that confirms the previous indirect observations of extrasolar planets.
Indirect observations are those where records of use are created through technology, such as logs of user interactions, logs of eye gaze, and so forth.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com