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"All have some efficacy.
We are all hoping the drug will have some efficacy, but our eyes are wide open.
Injections of fluorouracil, a compound used in cancer chemotherapy, has shown some efficacy in flattening small keloids.
Iodide and gentian violet have endured as therapeutic agents, while nystatin, an antifungal antibiotic, has shown some efficacy.
"What's been shown is that people with alcohol and cocaine problems have less GABA in their brains, and we do know that medications that increase GABA have shown some efficacy in treating addiction".
Gottlieb said GSK had previously abandoned a vaccine trial after finding the product was not effective against HSV-2, although it did show some efficacy against HSV-1.
Two of these have some efficacy data available indicating non-response to therapy.
Attention is now focusing on a vaccine for the Epstein Barr virus - and some efficacy has already been demonstrated.
Only open trials or case series showed some efficacy of gabapentin, topiramate and lamotrigine in controlling BPSD.
Dated findings on a limited number of patients support some efficacy of domperidone in preventing migraine attacks or reducing head pain intensity [326 328].
OnabotulinumtoxinA showed some efficacy in various open studies in migraine patients, but contradictory results emerged in double-blind controlled studies versus placebo concerning patients with episodic migraine [181].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com