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Since then, there has been some degeneration, with Mr. Epperson's original ingenuity swamped by unnecessary camp shenanigans.
Snowy-haired and diminutive at barely 5 feet, Ms. Eaton Travis, a lifelong Christian Scientist who frowns on medical care, is spry and sharp-witted, suffering only from elevated blood pressure for which she takes pills, and some degeneration of her sight and hearing.
When the exposure to S. venezuelae conditioned medium was extended to eight days, all neuronal classes exhibited some degeneration, but the DA neurons were still preferentially vulnerable compared to other neuronal classes (Fig. 2D) (P<0.05).
Alternatively, both genes may experience some degeneration and lose partial functionality, but can complement each other (sub-functionalization).
Furthermore, in 15-day-old animals, almost complete loss of photoreceptor neurons was found in GMR-HQ/ninaE>dnaJ-1 (GMR-HQ ninaE-Gal4/UAS-dnaJ-1) retinae, whereas many normal photoreceptors still remained in GMR-HQ/ninaE>dnaJ-1 hsc70cb (GMR-HQ ninaE-Gal4/UAS-dnaJ-1 UAS-hsc70cb) retinae, despite of some degeneration.
The strongly heteromorphic sex chromosomes of S. latifolia are likely to have evolved long enough ago for some degeneration to have occurred, and, like papaya, the YY genotype is inviable (Westergaard 1958; Janousek et al. 1998), so this species may therefore be suitable for studying degeneration.
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Some oligodendroglia cells adhering to blood vessels show symptoms of softening and some undergo degeneration.
"The fact that she is hard of hearing and suffers from some macular degeneration (entirely common for someone in their late 80s) has no bearing whatsoever on her quick wit, or of speaking her mind on all manner of things.
Histology demonstrated native RPE variably migrated onto the nanofibers, and a reactive gliosis with some photoreceptor degeneration.
Given that some present degeneration therapies incorporate biological regrowth of the nucleus pulposus (NP), it is crucial that the AF remains capable of containing this newly grown material.
While ectopic re-expression of SARM1 (C-terminal GFP tagged) in Sarm1−/− neurons (with normal NMNAT2) unexpectedly induced some neurite degeneration by 24 hr, it induced much more extensive degeneration of Nmnat2gtE/gtE; Sarm1−/− neurites (lacking NMNAT2) and, crucially, this was significantly reduced by co-expression of NMN deamidase (N-terminal GFP tagged).
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