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Some databases for drug-associated pathways have been built and are publicly available.
Some databases, for example HumanCyc, prefer to err on the side of false positives to bring potential pathways to the attention of the community [ 11].
At this stage we have not addressed the issue of quality of interactions although such information is available in some databases for some publications (23).
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The Base Server receives click stream records from the various first-servers, and obviously has to store them in some database for later processing.
First, the companion scores of some databases (BaliScore for BAliBASE, qscore for Prefab) were used in order to establish the absolute accuracy of each individual MSA tested in this study.
Some databases used for this purpose lack reference profiles for Brucella species, which is still an important pathogen in wide areas around the world.
The use of accurate and up-to-date databases is extremely important when analyzing a sample longitudinally; however, some statistical databases for past players have been found to be incomplete.
In the original annotation of Y. pestis CO92 [25], the Sanger Institute used ORPHEUS [43], WUBLAST [44], and FASTA [45] for predicting protein-coding regions and some InterPro databases for function annotation.
Many proteins such as membrane receptors and enzymes have been intensively studied as drug targets, and various biological information on the target proteins have been stored in some public databases, for example Therapeutic Target Database (5) and SuperTarget (6).
Arabidopsis thaliana, a small flowering plant with only several weeks of life cycle, has important advantages for the research of genetics and molecular biology, thus some special databases for Arabidopsis thaliana have been established.
Some databases are maintained for administrative reasons, while others are used for recording and reporting epidemiological data.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com