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In some cases, genes flanking a targeted locus might even fake phenotypic changes.
In 1998, Craig Mello and Andrew Fire, professors at the University of Massachusetts and the Carnegie Institution, published a stunning finding: in some cases, genes worked completely differently from the way scientists had thought.
In some cases, genes underlying the QTL have been identified.
In some cases, genes were only differentially expressed at one temperature.
In some cases, genes with a similar timing of expression were differentially clustered based on the transcript levels.
In contrast, although highly significant in some cases, genes whose expression is increasing with age are enriched a maximum of 1.80 fold (Table 4).
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Nanoceria was suggested in previous reports to exert effects on primary neural cells or cell lines, and in some cases, gene expression studies were conducted to shed light on the underlying mechanisms58, 62.
Optimally, all patients in the study should have had their tentative PCD diagnosis confirmed or refuted after the completion of both thorough clinical assessment, nasal NO measurement, EM, ciliary function testing, PRMC, and in some cases gene testing.
Despite the obvious benefits of this strategy, it is true that in some cases gene order within a particular chromosomal segment may not follow the ascending/descending order rule based on precedence of gene discovery; however, this shortcoming does not negate the value of the system as a whole.
In some cases, gene fragments were discovered in the first release of the genome (November 2003) and PCR was used to link the fragments together.
In some cases, gene synthesis with optimization of the codon usage of either the whole cDNA or its 5' end [45], [46] proved to be efficient means in order to increase the yield of protein production.
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