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Though many researchers have assumed the cause of Parkinson's is specific to the special nerve cells that are lost in the disease, Dr. Lindquist believed that some basic cellular process might be to blame, in which case it could best be explored first in yeast, a well-studied organism that is easy to manipulate in the lab.
It has also identified some basic cellular dependencies that may influence the expectations of the process.
The distribution characteristics of classifiers across tissues, chemicals, and TF networks suggested a differential biological impact among the chemicals on zebrafish transcriptome involving some basic cellular functions.
The distribution characteristics of classifiers across tissues, chemicals, and TF networks suggested a differential biological impact among the EDCs on zebrafish transcriptome involving some basic cellular functions.
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The cells of sap-feeding insects house a unique partnership—symbiotic bacteria provide essential amino acids to sap-sucking insects in exchange for a place to live and, in some cases, basic cellular housekeeping.
Core genes are those present in every genome, and include conserved essential genes for proteins such as actin, or polymerases, histones and ribosomal constituents required for some of the most basic cellular processes such as replication and translation.
In some studies, gene expression and basic cellular function of such ALI cultures were shown to resemble those found in vivo in intact bronchial epithelium [ 1, 17].
Although the fungi are very diverse in nature, their basic cellular physiology and genetics shares some common components with plants and animal cells.
The intrinsically unstructured state of some proteins, observed in all living organisms, is essential for basic cellular functions.
And for molecular biologists, models that are of sufficient accuracy will yield new understanding of basic cellular principles.
But if synuclein is involved in a basic cellular process like the packet delivery system, why should its toxic side effects only turn up in the dopamine-producing neurons of the brain?
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