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In addition, Sim2D between two molecules of the same family (with the same large core) may happen to be about 0.1, as it is the case for example of some actives of protein wee1.
Noteworthy, is the number of cases at the 0.25% fraction where the average enrichment factors were incalculable (using the equation described in the "Methods" section), as some actives as queries retrieved no negative hits in this fraction of top hits (Additional file 2: Figure S1; Additional file 3).
Similar(58)
The agglomeration may block some active sites, hence, significantly lower the ORR activity.
The antibacterial activity has been attributed to the presence of some active constituents in the oils.
There is also some active voter contact.
Some active ingredients can be compressed directly.
Some active Republicans said they had never heard of him.
But there are several efforts underway — some active, others dormant.
Some active ingredients had been weakened by more than 90%.
Suppose you're going back for some active point.
Well, to some active participants, their involvement seemed naive.
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