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Information for gene function categories such as "somatic stem cell maintenance" was extracted from the Gene Ontology Database58.
Kogler, G. et al. A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential.
Biteau, B., Hochmuth, C. E. & Jasper, H. Maintaining tissue homeostasis: dynamic control of somatic stem cell activity.
His laboratory studies genome regulation in carcinogenesis and stem cell differentiation by genomics and proteomics-based methods and discovered the first long non-coding RNAs involved in somatic stem cell differentiation and terminal epidermal differentiation.
Mesenchymal stem cells (MSCs) can be isolated from the bone marrow stroma where they constitute an adult somatic stem cell population distinct from hemapoietic stem cells.
BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary.
Thus, for best results, i.e., differentiation into cardiomyocytes, autologous adult somatic stem cell transplantation is needed.
Cancer stem cells have been proposed as slowly cycling cells, like their somatic stem cell counterparts [43].
The ABC transporter ABCG2 or its murine ontholog Bcrp1 may be regarded as another somatic stem cell marker.
We then used the model as a methodology for studying somatic stem cell self-renewing symmetric division mechanism.
Several research groups have shown Oct4 to be dispensable for somatic stem cell function and their expression by several biochemical experiments.
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