Sentence examples for somatic profiles from inspiring English sources

We and others have shown specific somatic profiles of CNAs characteristic for both BRCA1 and BRCA2-associated breast carcinomas [ 13– 17].

Under all conditions, only those cells in which a clear, well defined somatic profile could be seen were counted.

3) Patient Somatic Mutation Profiles: A table which records the mutation profile of each patient is also included in our framework as background information.

Intra- and inter-tumor heterogeneity may hinder personalized molecular-target treatment that depends on the somatic mutation profiles.

The number of clones with the R46X mutation was statistically significantly overrepresented only in the T-ALL cell lines relative to the random somatic mutation profiles [15] (Table 1).

Using the Gene Expression Commons (GEXC) tool, we compared these gene sets to existing germline, embryonic, and somatic expression profiles.

This results in somatic mutational profiles for 3,096 patients with mutations in 19,171 genes (mapped to the Entrez Genes).

First, the somatic mutation profiles from both the COSMIC and TCGA are mixed with driver and passenger mutations.

No association was evident between somatic symptom profiles and body mass index, physical activity level, or smoking status.

We use hierarchical clustering of somatic mutation profiles randomly sampled from the COSMIC resource to identify high multiplicity similarities in somatic mutation patterns across cancer types.

In this study, we developed a protein pocket-based approach by incorporating large-scale somatic mutation profiles into the protein pocket regions.