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"Embryonic stem cells generated by nuclear transfer of human somatic nuclei into rabbit oocytes".
Precise anatomical data on the development of human oculomotor somatic nuclei (OSN) remain rare.
A consistent feature of sperm nuclei is its exceptionally compact state in comparison with somatic nuclei.
In the far future, perhaps somatic nuclei could be reprogrammed directly.
There are 959 somatic nuclei in an adult hermaphrodite, and consequently considerably less in its various tissues.
Our data demonstrated that telophase enucleation is beneficial to early embryo development when bovine somatic nuclei are transferred by subzonal injection.
Genome architecture varies considerably among eukaryotes in terms of both size and structure (e.g. distribution of sequences within the genome, elimination of DNA during formation of somatic nuclei).
The presence of both germline and somatic nuclei in these cells requires different strategies to target DNA to the desired compartment.
Despite remarkable progress in the cloning of mammals using different somatic nuclei, there is little information available regarding the choice of donor cell origin (type and/or gender) for mammalian somatic cell nuclear transfer.
The ability of pluripotent stem cells to reprogram somatic nuclei to a primitive, pluripotent state increases the potential of achieving somatic cell reprogramming in an efficient manner for therapeutic purposes without resorting to nuclear transfer to oocytes, so-called therapeutic cloning.
Approximately one third of somatic nuclei in the adult are found in syncytia [52].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com