Among the TOP10 solutions, clusters L3 and L1 represent 17% and 10%, respectively.
Among the 30 best-scored solutions, five solutions clustered and were also compatible with all constraints mentioned above (Appendix figure 6), including the observation that the C2 domain does not contribute to binding.
In the four-cluster solution, cluster sizes varied from 7 to 34.
In the three-cluster solution, cluster A had a high score for 'Team leader' and a low score for 'Primary nurse'.
Based upon the proposed stochastic initiation strategy and solution clustering method, an efficient algorithm is developed to obtain the global optimum of this MINLP model with high creditability.
In this paper, the stable solid solution cluster-plus-glue-atom model was used to design the composition of Cu seed layers.
The study of the two-parameter model allows us to show the connection between multiple solutions for noise-free data and solution clustering for noisy data.
We also tested the robustness of the clustering solutions by conducting cluster analysis on subgroups of patients defined by gender, ethnicity, age group and injury type.
We find that in homopolymer solutions, the cluster size reaches a minimum at a specific chain molecular weight (MW).
Alternative solutions with Clusters 4 and 5 showed specific discrimination of cluster 1 by gender and dental education professionals.
The presented JavaScript library InCHlib is a client-side solution for cluster heatmap exploration.
