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An extended investigation of homogeneous fluidization of Geldart's group B solids was conducted in two packed columns (5 and 10 cm OD) whose packing spheres were either 0.41 cm lead shots or 1.1 cm glass beads.
Liquefaction of the solids was conducted at 50°C and 200 rpm.
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Analyses of scanning electron microscopy (SEM) and X-ray diffraction (XRD) of the resulting solids were conducted to characterize changes in mineral phases.
Enzymatic hydrolyses of the washed solids were conducted at 2% (w/ v) in 50 mL of 50 mM acetate buffer (pH 5.5) on a shake/incubator (Thermo Fisher Scientific, Model 4450, Waltham, MA) at 50°C and 200 rpm.
An experimental method to study the effects of this procedure on the thermal pilot furnace, which was specially designed to burn pulverized solid fuel, was conducted.
As population-specific data are critically needed to optimise dosing from a safety perspective owing to potential ethnic differences, this phase I study of escalating doses of volasertib administered to Asian patients with advanced solid malignancies was conducted.
In total, these non-clinical studies suggest that TAK-285 may possess exploitable antineoplastic activity and consequently a phase I first-in-human study in patients with solid tumours was conducted in Japan.
A phase I/II trial of Valproate in combination with Epirubicin or the combination of 5-Fluorouracil, Epirubicin, and Cyclophosphamide (FEC100) for patients with solid tumors was conducted by Munster et al. (2009b).
Solid state fermentation was conducted using various solid substrates and agricultural residues.
SOLiD System templated bead preparation and sequencing on the SOLiD 4.0 system was conducted by CeGaT GmbH (Tübingen, Germany).
Solid state cultivation was conducted and the crude enzyme mixture was extracted as described in the previous research [ 13].
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