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Following his approach from MC and complementing it with occasional references to his EAC, Kepler makes use again of the Platonic solids to determine the number of the planets and their distances from the Sun.
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Previous studies have suggested that naproxen may be safer than other types of NSDAIDs, but the more recent evidence reviewed by the expert panel isn't solid enough to determine that for certain.
The comparison between experimental and theoretical results provides solid ground to determine the accuracy of the available model for the the prediction of the steady-state behavior of the tilting-pad bearing with controllable lubrication.
Test results and finite element analysis (FEA) results were compared with calculated values based on current ACI design practice and other available design formulations developed for solid walls to determine if these empirical formulae are also applicable for sandwich panels.
This dose-escalation study was conducted according to the Chinese State Food and Drug Administration SFDAA) recommendations in patients with advanced solid tumors to determine the MTD for orally administered apatinib.
Hence, we have used high-throughput SOLiD sequencing to determine potential changes in the miRNA transcriptome in Senegalese sole embryos that were incubated at 15°C or 21°C until hatching and then reared at a common temperature of 21°C.
Additional use of a molecular investigation, such as RT PCR, has been largely developed in various solid tumours to determine the incidence of micrometastases missed during routine light microscopy (Ambrosch and Brinck, 1996).
In this phase I trial, we evaluated the safety, tolerability and pharmacokinetics of sagopilone in patients with heavily pretreated solid tumours, to determine the maximum tolerated dose (MTD) and dose-limiting toxicities (DLTs) of a weekly treatment schedule.
Phase 1b study in patients with EpCAM-positive advanced solid tumors to determine the maximum tolerated dose (MTD) and safety profile of huKS-IL2 in combination with low-dose cyclophosphamide.
The objectives of this phase I study were to assess the safety and tolerability of E7080 in patients with advanced, refractory solid tumours; to determine the maximum tolerated dose (MTD) and pharmacokinetics profile of E7080; and to explore preliminary evidence of its anti-tumour efficacy.
The washed solids were collected to determine moisture content and calculate the solid recovery from IL pretreatment.
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