There will be foreplay, followed by a gentle lead up to solid yet exciting stimulus, that will inspire the economy to put out over a long period of time rather than in a single tidal wrack of explosive discharge.
By definition, the average response to the Eff stimulus (solid line) was greater than the average response to the Ineff stimulus (dashed line) (Fig. 2 a ).
Dotted lines denote low featural complexity stimuli, with solid lines as high featural complexity stimuli.
The story was already entrenched in our consciousness, and will be with us until we see a real, solid boost from the stimulus package and its likely successors.
This was predicted to be correlated with the high levels of distortional strain transferred through the solid component of the stimulus.
Figure 3 shows an example of the responses to the first 10 stimuli (gray dashed line) and to the last 10 stimuli (black solid line) of the training protocol in a successful experiment.
Despite our limited knowledge on the pathway, there are increasing discoveries of new molecules that regulate and modulate the Hippo downstream signaling particularly in various solid malignancies, from extracellular stimuli or via pathway crosstalk.
Interactions between tumour cells and components of the ECM can protect solid tumours from toxic stimuli [ 30- 33].
Models capable of calculating drug penetration and resulting concentration profiles may be of particular importance to accurately replicate spatiotemporal profiles of apoptosis-inducing stimuli in solid tumours.
