Sentence examples for solid state stability from inspiring English sources
Based on the solid state stability and kinetic solubility of the MBP, hydroxypropylmethylcellulose acetate succinate polymer with 40% or lower drug loading, and antisolvent (0.01 N HCl) to solvent (dimethylacetamide) ratio of 5 1 or higher were selected to make glybenclamide MBP.
c Solid state stability analysis.
Atazenavir bisulfate exhibited distinct advantage over other salts such as methane sulfonate and hydrochloride in terms of solubility and solid state stability.
Reported advantages offered by cocrystallization include superior stability under stress condition [ 12], enhanced purification efficiency [ 15], improvement in chemical stability [ 16], superior solid state stability than salts [ 17], improved dissolution performance, enhanced bioavailability [ 18], and better tabletability [ 19, 20].
Instead, API amorphous form may be used, since the apparent solubility of crystalline form is not better than that of the amorphous form; however, the solid state stability concerns and problems related to scale-up methods still present barriers to formulation development [ 8].
ME applications include taste masking, solid-state stability enhancement, sustained drug release and solubility enhancement.
Melibiose is a better candidate than isomalt because of easier processability and superior solid-state stability.
The impact of process parameters on yield and solid-state stability was compared to sucrose and trehalose.
As such, due to the long half-life of CFZ and high solid-state stability as non-toxic crystals, CFZ formulations could be designed for long-term monitoring of the joint via a single injection alone.
5-Fluorocytosine (FC) is a high-dose antifungal drug that challenges the development of a tablet product due to poor solid-state stability and tabletability.
Solid crystalline phases containing two cocrystallized components offer a new development pathway whereby one can potentially improve the physical characteristics (i.e., equilibrium solubility, dissolution rate, solid-state stability, etc). of a drug substance that exhibits a profile that is less than desirable.
