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Severe leakage of drilling fluid and reservoir damage due to water and solid invasion during well drilling are the key factors that restrict economic exploitation of coal bed methane (CBM) in China.
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For melanomas (Rofstad et al. 2006), it has been assumed that the acid mediates the solid tumour invasion by remodelling the adjacent normal tissues that allow local invasion.
In the model, solid particle invasion and irreducible water saturation are taken into account.
Based on the test results, the factors causing damage to the tight sandstone gas reservoir included solid phase invasion to fractures, wettability alteration, oil phase trapping and emulsion plugging.
Generally, solid-phase invasion, fines migration, scale formation, and water sensitivity (Chen and Dai 2005; Wu et al. 2007; Buchsteiner 1993; Sadeghazad and Beiranvand 2003) can cause pollution and plugging near the wellbore which has adverse effects on oil production.
Due to solid-phase invasion, fines migration, scale formation, and water sensitivity, the formation near the wellbore can be easily polluted and plugged, resulting in a lower fluid production and serious heterogeneity.
There are three main ways for dissemination of solid tumors: direct invasion, lymphatic spread and hematogenic spread.
Angiogenesis is an essential step in solid tumour development, invasion, and metastasis.
The morphologic patterns, predominant histologic subtypes (lepidic, acinar, papillary, micropapillary, cribriform, and solid), presence of lymphovascular invasion, pleural invasion, and other clinical data were recorded.
Upon confirmation of neither lymphovascular invasion nor solid organ metastases, we decided to proceed with Whipple's procedure.
It is shown that the underbalanced drilling is beneficial to reservoir protection because of its less damage on reservoir permeability, but it is, to some extent, sensitive to the stress and the empirical formula of stress sensitivity coefficient is obtained; and that the overbalanced drilling has more reservoir damages due to the invasion of solid and liquid phases.
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