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Through a variety of approaches (autoradiography, saturation binding and western blotting) recent studies have shown an increase in total serotonin 2C receptor expression in mice engineered to solely express the fully edited (Valine-Glycine-Valin, VGV) form of the 5-HT2C receptor (Kawahara et al., 2008; Morabito et al., 2010a; Olaghere da Silva et al., 2010).
My visual sensibilities tend to form an emotionality that is beyond my control, visceral feelings which I can solely express through artistry.
As the INI mice solely express the unedited form of the 5-HT2C recepthroughouthout life, there may be compensations within serotonin networks that underpin the observed phenotype.
As an additional control, we measured the crawling speeds of untreated worms that solely express YFP in their muscles (polyQ0-YFP).
PCR genotyping of the purified IMCs confirmed that they contained the unrecombined LSL-V600E allele but not the recombined Lox-V600E allele (Fig 2F), indicating that they solely express WTBRAF and not V600EBRAF, and thus accumulate as a reactive response to the oncogene-expressing lung tumours.
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Support was provided by the tissue expression in rat, where the protein is solely expressed in cilia-containing tissues, including testis, cultured ependymal cells, lung and brain.
CelA1 was solely expressed during secondary wall cellulose synthesis, with no significant expression difference between TM-1 and Hai7124 (Additional file 6: Supplemental Figure S3C).
In Berberis julianae, we found that AGL6 is solely expressed in the floral tissue (BjAGL6, Figure 3e), similar to SEP3 expression (BjSEP3, Figure 3f).
No GFP expression in glia was detected in these embryos, indicating that elavGal4 was solely expressed in neurons.
Due to genomic imprinting, UBE3A is solely expressed from the maternal allele in neurons.
The finding that sensory neuron-specific G-protein-coupled receptor mRNA is solely expressed in small primary sensory neurons suggests involvement of the receptor in nociceptive modulation.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com