Exact(2)
In contrast, both antibodies detected PsVs in the interior of permeabilized cells (Figure 1, 12 h, MetOH; Figure S2, PFA+Triton or MetOH), indicating that the L1-7 episope isolelyly accessible in the cellular interior after entry.
This implies that the aggregation pathway consists of two steps: the first, only requiring the JD, gives rise to SDS-soluble protofibrils, whereas the second is solely accessible to variants carrying expanded polyQs and results in the formation of mature, SDS-insoluble fibrils [12], [13].
Similar(6)
They are among the northernmost of the Florida keys and the only ones of any size that are accessible solely by boat.
Their statement added: "We oppose cuts that will result in university institutions being a privilege accessible solely to the few.
Recently the Parks Department fenced off a large section of Tompkins Square Park, making it accessible solely for parents and children.
Jessica Lapidos of Tilly and William, a unisex label, was one of the first of some 40-odd designers who have already signed up, pleased by the promise of technology "typically accessible solely to big businesses," she said, like pattern-making software, photo-studio space and sales representation.
The list of study identification numbers linked to a given colour was kept locked and was accessible solely to the pharmaceutical technician preparing doses.
The randomization is accessible solely by the independent researcher.
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