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Thus, out of a total of 16 cysteine residues, Brf2 C361 is the sole reactive cysteine negatively regulating the formation of the Brf2-TBP/DNA ternary complex upon alkylation.
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The peptide NF04 (structurally derived from an oxidoreductase enzyme), which was found to be the sole potently reactive compound among tested molecules, was further evaluated in a peptide-based enzyme-linked immunosorbent assay (peptide-based ELISA), thus confirming its specific interaction with ochratoxin A.
It promotes design exploration by means of a synthesis approach with the sole aim of producing reliable reactive systems.
We previously reported that high glucose milieu enhances expression of angiotensinogen (AGT, the sole precursor of all angiotensins) through generation of reactive oxygen species (ROS) in cultured rat renal proximal tubular cells (RPTCs) [ 17, 18].
Until recently, the combination of early detection, case management, and reactive immunization using polysaccharide vaccines were the sole approaches available to control these epidemics.
HIV-1 vaccine development has been stymied by an inability to induce broadly reactive neutralizing antibodies to the envelope (Env) trimer, the sole viral antigen on the virion surface.
At higher temperature, higher amounts of reactive nitrogen intermediates may be endogenously generated, in particular during growth with nitrate as sole nitrogen source.
Therefore, our findings suggest that IRF8 is not the sole transcription factor for microglial activation but rather activates a program of gene expression that determines signaling activity of reactive microglia, which provides a newly observed mechanism for microglial activation.
And sole.
We are reactive traditionalists.
"They have been reactive".
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